The Most Important Blood Tests You Should Take at Least Once a Year - and Why Early Prevention Can Save Lives

Най-важните кръвни изследвания, които трябва да правим поне веднъж годишно — и защо ранната профилактика може да спаси живот
In modern medicine, there is a clear trend: prevention is more effective and less invasive than treatment. Many diseases begin “silently,” without symptoms — and this is where regular blood tests can prevent serious consequences. Regular monitoring of key indicators is not only “for sick people.” It is smart healthcare, regardless of age or lifestyle. In this article, we’ll look at which blood tests are essential to do at least once a year, what they show, and how they can “catch” a problem before it appears. 1. CBC (Complete Blood Count) — the foundation of health This is the most commonly prescribed test — and for good reason. It provides information about:
  • anemia (low hemoglobin / iron levels)
  • inflammatory processes
  • bone marrow disorders
  • immune responses
Why it matters: Anemia can lead to fatigue, arrhythmia, and weakened immunity. Inflammation can be an early sign of infection or chronic disease. 2. Lipid Profile (LDL, HDL, Triglycerides) — the heart’s risk zone This panel shows whether your cardiovascular system is at risk.
  • LDL (“bad”) cholesterol → builds up in arteries
  • HDL (“good”) cholesterol → has a protective effect
  • Triglycerides → often elevated with insulin resistance and poor diet
Risk: Heart attack, stroke, and atherosclerosis — often symptom-free until it’s too late. 3. Blood Sugar / HbA1c — prediabetes starts silently Testing fasting glucose and especially HbA1c reveals a tendency toward prediabetes.
  • HbA1c shows average blood sugar levels over the past 3 months
  • the most reliable marker for long-term control
Important: Many people don’t know they have prediabetes — it’s often discovered by chance. 4. TSH, T3, T4 — thyroid hormones The thyroid affects energy, weight, mood, menstrual cycle, sleep, and metabolism. Symptoms usually appear late — testing is more reliable than guessing. 5. Liver Enzymes (AST, ALT, GGT) The liver is an organ that doesn’t hurt until problems become serious. Elevated enzymes can indicate:
  • fat buildup (steatosis)
  • toxic overload
  • inflammation or hepatitis
6. Kidney Function (Creatinine, Urea, GFR) Kidney disease often begins without visible symptoms. Monitoring creatinine and GFR (filtration rate) is essential, especially for:
  • high blood pressure
  • diabetes
  • frequent medication use
7. Vitamin D and Vitamin B12 — essential for immunity and the nervous system A lack of vitamin D is linked to:
  • higher risk of infections
  • depressive states
  • autoimmune diseases
And low levels of vitamin B12 are linked to anemia, neurological symptoms, and chronic fatigue. How often? The smart rule
  • At least once a year — if you have no complaints
  • Every 6 months — if you have risk factors (overweight, family history, chronic illness)
  • Immediately — if you experience unusual fatigue, unstable weight, hormonal changes, or low energy
Conclusion: Prevention is a form of strength, not fear True professionalism — in both medicine and personal health care — lies in foresight, not in reaction after problems occur.